Anders Bach
Professor
Medicinal Chemistry
Jagtvej 162
2100 København Ø
- 2024
- Published
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Fadahunsi, N., Petersen, J. O., Metz, S., Jakobsen, A., Mathiesen, C. V., Buch-Rasmussen, A. S., Kurgan, N. K., Larsen, J. K., Andersen, R. C., Topilko, T., Svendsen, C., Apuschkin, M., Skovbjerg, G., Schmidt, J. H., Houser, G. A., Jager, S. E., Bach, A., Deshmukh, A. S., Kilpeläinen, T. O., Strømgaard, K. & 2 others, , 2024, In: Science Advances. 10, 9, 20 p., eadg2636.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Advances in developing noncovalent small molecules targeting Keap1
Barreca, M., Qin, Y., Cadot, Marie Elodie Hélène, Barraja, P. & Bach, Anders, 2023, In: Drug Discovery Today. 28, 12, 25 p., 103800.Research output: Contribution to journal › Review › Research › peer-review
- Published
Small-molecule modulators of tumor necrosis factor signaling
Chédotal, H., Narayanan, Dilip, Povlsen, K., Gotfredsen, C. H., Brambilla, R., Gajhede, Michael, Bach, Anders & Clausen, M. H., 2023, In: Drug Discovery Today. 28, 6, 103575.Research output: Contribution to journal › Review › Research › peer-review
- Published
In Vitro and In Vivo Evaluation of Pellotine: A Hypnotic Lophophora Alkaloid
Poulie, C. B. M., Chan, C. B., Parka, A., Lettorp, M., Vos, J., Raaschou, A., Pottie, E., Bundgaard, M. S., Sørensen, L. M. E., Cecchi, C. R., Märcher-Rørsted, E., Bach, A., Herth, M. M., Decker, A., Jensen, A. A., Elfving, B., Kretschmann, A. C., Stove, C. P., Kohlmeier, K. A., Cornett, C. & 3 others, , 2023, In: ACS Pharmacology & Translational Science. 6, 10, p. 1492-1507Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The European Federation for Medicinal Chemistry and Chemical Biology (EFMC) Best Practice Initiative: Hit Generation
Quancard, J., Vulpetti, A., Bach, Anders, Cox, B., Guéret, S. M., Hartung, I. V., Koolman, H. F., Laufer, S., Messinger, J., Sbardella, G. & Craft, R., 2023, In: ChemMedChem. 18, 9, e202300002.Research output: Contribution to journal › Review › Research › peer-review
- Published
Chemical synthesis of a reported p47phox/p22phox inhibitor and characterization of its instability and irreproducible activity
Zang, J., Cambet, Y., Jaquet, V. & Bach, Anders, 2023, In: Frontiers in Pharmacology. 13, 9 p., 1075328.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting NOX2 with Bivalent Small-Molecule p47phox-p22phox Inhibitors
Zang, J., Peters, F., Cambet, Y., Cifuentes-Pagano, E., Hissabu, M. M. S., Dustin, C. M., Svensson, L. H., Olesen, M. M., Poulsen, M. F. L., Jacobsen, Stig, Tuelung, P. S., Narayanan, Dilip, Langkilde, Annette Eva, Gajhede, Michael, Pagano, P. J., Jaquet, V., Vilhardt, Frederik & Bach, Anders, 2023, In: Journal of Medicinal Chemistry. 66, 21, p. 14963–15005Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening
Lee, S., Tran, K. T., Vazquez-Uribe, R., Gotfredsen, C. H., Clausen, M. H., Mendez, B. L., Montoya, Guillermo, Bach, Anders & Sommer, M. O. A., 2022, In: Journal of Medicinal Chemistry. 65, 4, p. 3266–3305Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Cell-Penetrating Peptide Tat Facilitates Effective Internalization of PSD-95 Inhibitors Into Blood–Brain Barrier Endothelial Cells but less Efficient Permeation Across the Blood–Brain Barrier In Vitro and In Vivo
Lisa Al Humaidan, E., Lund Pedersen, S., Burkhart, A., Laurfelt Munch Rasmussen, C., Moos, T., Fuchs, P., Alves Fernandes, E. F., Ozgür, Burak, Strømgaard, K., Bach, Anders, Larsen, Birger Brodin & Kristensen, Mie, 2022, In: Frontiers in Drug Delivery - CNS Drug Delivery. 2, 17 p., 854703.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of Noncovalent Small-Molecule Keap1-Nrf2 Inhibitors by Fragment-Based Drug Discovery
Narayanan, Dilip, Tran, K. T., Pallesen, J. S., Solbak, S. M. Ø., Qin, Y., Mukminova, E., Luchini, M., Vasilyeva, K. O., González Chichón, D., Goutsiou, G., Poulsen, C., Haapanen, N., Popowicz, G. M., Sattler, M., Olagnier, D., Gajhede, Michael & Bach, Anders, 2022, In: Journal of Medicinal Chemistry. 65, 21, p. 14481-14526Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1304261
Most downloads
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2786
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PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Research output: Contribution to journal › Journal article › Research › peer-review
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290
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A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
165
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Molecular architecture of the Jumonji C family histone demethylase KDM5B
Research output: Contribution to journal › Journal article › Research › peer-review
Published