Multifocal central serous chorioretinopathy with photoreceptor-retinal pigment epithelium diastasis in heritable pulmonary arterial hypertension

Research output: Contribution to journalJournal articlepeer-review

PURPOSE: To report atypical central serous chorioretinopathy and choroidal thickening in a patient with heritable pulmonary arterial hypertension.

METHODS: A 40-year-old man with heritable pulmonary arterial hypertension presented with blurred vision in his left eye and was followed up for 1 year with clinical examination, enhanced depth optical coherence tomography, fluorescein and indocyanine green angiography, and fundus photography.

RESULTS: At presentation, atypical central serous chorioretinopathy with multiple retinal pigment epithelial detachments, a thick subfoveal choroid, and dilated choroidal vessels were seen in the patient's symptomatic left eye. After treatment for pulmonary hypertension, the serous detachments disappeared and choroidal thickness gradually decreased over a period of 4 weeks and remained unchanged at 13 months of follow-up.

CONCLUSION: Central serous chorioretinopathy and choroidal thickening that responded to treatment of pulmonary arterial hypertension suggest a pathophysiological link between pulmonary arterial hypertension and central serous chorioretinopathy, perhaps mediated by choroidal venous stasis.

Original languageEnglish
JournalRetinal Cases & Brief Reports
Volume9
Issue number1
Pages (from-to)83-7
Number of pages5
ISSN1935-1089
DOIs
Publication statusPublished - 2015

    Research areas

  • Adult, Central Serous Chorioretinopathy, Choroid Diseases, Humans, Hypertension, Pulmonary, Male, Retinal Detachment, Retinal Pigment Epithelium

ID: 160797738