An introduction with medical applications to functional data analysis

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Functional data are data that can be represented by suitable functions, such as curves (potentially multi-dimensional) or surfaces. This paper gives an introduction to some basic but important techniques for the analysis of such data, and we apply the techniques to two datasets from biomedicine. One dataset is about white matter structures in the brain in multiple sclerosis patients; the other dataset is about three-dimensional vascular geometries collected for the study of cerebral aneurysms. The techniques described are smoothing, alignment, principal component analysis, and regression.
Original languageEnglish
JournalStatistics in Medicine
Volume32
Issue number30
Pages (from-to)5222-5240
Number of pages19
ISSN0277-6715
DOIs
Publication statusPublished - 2013

ID: 87416948