Sequential transcriptome analysis of human liver cancer indicates late stage acquisition of malignant traits
Research output: Contribution to journal › Journal article › Research › peer-review
Human hepatocarcinogenesis is as a multi-step process starting from dysplastic lesions to early carcinomas (eHCC) that ultimately progress to HCC (pHCC). However, the sequential molecular alterations driving malignant transformation of the pre-neoplastic lesions are not clearly defined. This lack of information represents a major challenge in the clinical management of patients at risk.
Original language | English |
---|---|
Journal | Journal of Hepatology |
Volume | 60 |
Issue number | 2 |
Pages (from-to) | 346-53 |
Number of pages | 8 |
ISSN | 0168-8278 |
DOIs | |
Publication status | Published - Feb 2014 |
Externally published | Yes |
ID: 108633068