Genetic Predisposition Increases the Tic Severity, Rate of Comorbidities, and Psychosocial and Educational Difficulties in Children With Tourette Syndrome
Research output: Contribution to journal › Journal article › Research › peer-review
This study aimed to examine whether there are differences in tic severity, comorbidities, and psychosocial and educational consequences in children with Tourette syndrome and genetic predisposition to Tourette syndrome compared with children with Tourette syndrome without genetic predisposition to Tourette syndrome. A total of 314 children diagnosed with Tourette syndrome participated in this study. Validated diagnostic tools were used to assess tic severity, comorbidities, and cognitive performance. A structured interview was used to evaluate psychosocial and educational consequences related to Tourette syndrome. The children with Tourette syndrome and genetic predisposition present with statistically significant differences in terms of severity of tics, comorbidities, and a range of psychosocial and educational factors compared with the children with Tourette syndrome without genetic predisposition. Professionals need to be aware of genetic predisposition to Tourette syndrome, as children with Tourette syndrome and genetic predisposition have more severe symptoms than those children with Tourette syndrome who are without genetic predisposition.
Original language | English |
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Journal | Journal of Child Neurology |
Volume | 30 |
Issue number | 3 |
Pages (from-to) | 320-325 |
Number of pages | 6 |
ISSN | 0883-0738 |
DOIs | |
Publication status | Published - Mar 2015 |
- Adolescent, Attention Deficit Disorder with Hyperactivity, Child, Cognition Disorders, Comorbidity, Education, Female, Genetic Predisposition to Disease, Humans, Learning Disorders, Male, Obsessive-Compulsive Disorder, Retrospective Studies, Severity of Illness Index, Tic Disorders, Tourette Syndrome
Research areas
ID: 152267674