Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets
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Proghrelin, produced by the ghrelin (A-like) cells of the gastric mucosa, gives rise to cleavage products, including desacyl ghrelin, acyl ghrelin and obestatin. The products are thought to be secreted concomitantly. In an earlier study we found acyl ghrelin and obestatin, but not desacyl ghrelin, to suppress the release of hormones from isolated islets of mouse and rat pancreas.
| Translated title of the contribution | Proghrelin peptides: Desacyl ghrelin is a powerful inhibitor of acylated ghrelin, likely to impair physiological effects of acyl ghrelin but not of obestatin A study of pancreatic polypeptide secretion from mouse islets |
|---|---|
| Original language | English |
| Journal | Regulatory Peptides |
| Volume | 164 |
| Issue number | 2-3 |
| Pages (from-to) | 65-70 |
| Number of pages | 6 |
| ISSN | 0167-0115 |
| DOIs | |
| Publication status | Published - 2010 |
ID: 34372190