Alemtuzumab for patients with relapsing multiple sclerosis after disease-modifying therapy: a randomised controlled phase 3 trial

Research output: Contribution to journalJournal articleResearchpeer-review

  • Alasdair J Coles
  • Cary L Twyman
  • Douglas L Arnold
  • Jeffrey A Cohen
  • Christian Confavreux
  • Edward J Fox
  • Hans-Peter Hartung
  • Eva Havrdova
  • Krzysztof W Selmaj
  • Howard L Weiner
  • Tamara Miller
  • Elizabeth Fisher
  • Rupert Sandbrink
  • Stephen L Lake
  • David H Margolin
  • Pedro Oyuela
  • Michael A Panzara
  • D Alastair S Compston
  • CARE-MS II investigators
  • Sørensen, Per Soelberg
The anti-CD52 monoclonal antibody alemtuzumab reduces disease activity in previously untreated patients with relapsing-remitting multiple sclerosis. We aimed to assess efficacy and safety of alemtuzumab compared with interferon beta 1a in patients who have relapsed despite first-line treatment.
Original languageEnglish
JournalLancet
Volume380
Issue number9856
Pages (from-to)1829-39
Number of pages11
ISSN0140-6736
DOIs
Publication statusPublished - 2012

ID: 48584402