Recently introduced qacA/B genes in Staphylococcus epidermidis do not increase chlorhexidine MIC/MBC

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Chlorhexidine is used as a disinfectant to prevent surgical infections. Recently, studies have indicated that chlorhexidine usage has selected methicillin-resistant Staphylococcus aureus strains that are tolerant to chlorhexidine and that this may be related to the presence of the qacA/B-encoded efflux pumps. Here, we evaluated if high-level exposure to chlorhexidine selects for tolerant colonizing Staphylococcus epidermidis and we addressed the consequences of long-term exposure to chlorhexidine.
Original languageEnglish
JournalThe Journal of antimicrobial chemotherapy
Volume68
Issue number10
Pages (from-to)2226-2233
Number of pages8
ISSN0305-7453
DOIs
Publication statusPublished - 2013

ID: 99349527