Association between DPP6 polymorphism and the risk of progressive multiple sclerosis in Northern and Southern Europeans

Research output: Contribution to journalJournal articleResearchpeer-review

  • Paola Brambilla
  • Federica Esposito
  • Eva Lindstrom
  • Melissa Sorosina
  • Giacomo Giacalone
  • Ferdinando Clarelli
  • Mariaemma Rodegher
  • Bruno Colombo
  • Lucia Moiola
  • Angelo Ghezzi
  • Ruggero Capra
  • Laura Collimedaglia
  • Gabriella Coniglio
  • Elisabeth G Celius
  • Daniela Galimberti
  • Vittorio Martinelli
  • Annette B Oturai
  • Hanne F Harbo
  • Jan Hillert
  • Giancarlo Comi
  • Filippo Martinelli-Boneschi
In this study, we investigated the role of the dipeptidyl-peptidase-6 (DPP6) gene in the etiopathogenesis of progressive forms of multiple sclerosis (PrMS). This gene emerged as a candidate gene in a genome-wide association study (GWAS) performed in an Italian sample of PrMS and controls in which two SNPs located in the gene (rs6956703 and rs11767658) showed evidence of association (nominal p-value
Original languageEnglish
JournalNeuroscience Letters
Volume530
Issue number2
Pages (from-to)155-60
Number of pages6
ISSN0304-3940
DOIs
Publication statusPublished - 2012

ID: 48584534