ABC transporter genes and risk of type 2 diabetes: a study of 40,000 individuals from the general population

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Alterations of pancreatic β-cell cholesterol content may contribute to β-cell dysfunction. Two important determinants of intracellular cholesterol content are the ATP-binding cassette (ABC) transporters A1 (ABCA1) and -G1 (ABCG1). Whether genetic variation in ABCA1 and ABCG1 predicts risk of type 2 diabetes in the general population is unknown.
Original languageEnglish
JournalDiabetes Care
Volume35
Issue number12
Pages (from-to)2600-6
Number of pages7
ISSN0149-5992
DOIs
Publication statusPublished - 2012

ID: 48541955