Synovial sarcoma mechanisms: a series of unfortunate events
Research output: Contribution to journal › Journal article › peer-review
Human synovial sarcoma is caused by a chromosome translocation, which fuses DNA encoding SSX to that encoding the SS18 protein. Kadoch and Crabtree now show that the resulting cellular transformation stems from disruption of the normal architecture and function of the human SWI/SNF (BAF) complex.
Original language | English |
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Journal | Cell |
Volume | 153 |
Issue number | 1 |
Pages (from-to) | 11-2 |
Number of pages | 2 |
ISSN | 0092-8674 |
DOIs | |
Publication status | Published - 28 Mar 2013 |
ID: 47713001