What can be learned from the history of recurrence in migraine? A comment
Research output: Contribution to journal › Journal article › Research › peer-review
Recurrence was first recognised as a clinical problem in 1989 with the advent of sumatriptan. The history of recurrence in early sumatriptan randomised clinical trials is described. Recurrence has been ascribed to patient-dependent factors but experience with ergot alkaloids suggested that recurrence can also be treatment-dependent. Possible mechanisms for recurrence are discussed.
Original language | English |
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Journal | Journal of Headache and Pain |
Volume | 10 |
Issue number | 5 |
Pages (from-to) | 311-5 |
Number of pages | 4 |
ISSN | 1129-2369 |
DOIs | |
Publication status | Published - 2009 |
Bibliographical note
Keywords: Clinical Trials as Topic; Humans; Migraine Disorders; Recurrence; Sumatriptan; Vasoconstrictor Agents
ID: 21405522