Pseudo-observations for competing risks with covariate dependent censoring

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Regression analysis for competing risks data can be based on generalized estimating equations. For the case with right censored data, pseudo-values were proposed to solve the estimating equations. In this article we investigate robustness of the pseudo-values against violation of the assumption that the probability of not being lost to follow-up (un-censored) is independent of the covariates. Modified pseudo-values are proposed which rely on a correctly specified regression model for the censoring times. Bias and efficiency of these methods are compared in a simulation study. Further illustration of the differences is obtained in an application to bone marrow transplantation data and a corresponding sensitivity analysis.

Original languageEnglish
JournalLifetime Data Analysis
Volume20
Issue number2
Pages (from-to)303-15
Number of pages13
ISSN1380-7870
DOIs
Publication statusPublished - Apr 2014

ID: 134781594