Expression of metastasin S100A4 is essential for bone resorption and regulates osteoclast function

Research output: Contribution to journalJournal articleResearchpeer-review

  • Malin C Erlandsson
  • M Svensson
  • Ing-Marie Jonsson
  • Li Bian
  • Noona Ambartsumian
  • Sofia Andersson
  • Zhiqi Peng
  • Jukka Vääräniemi
  • Claes Ohlsson
  • Karin M E Andersson
  • Maria I Bokarewa
S100A4 is a Ca-binding protein that regulates cell growth, survival, and motility. The abundant expression of S100A4 in rheumatiod arthritis contributes to the invasive growth of joint tissue and to bone damage. In the present study, we analysed the role of S100A4 in bone homeostasis.
Original languageEnglish
JournalBBA General Subjects
Volume1833
Issue number12
Pages (from-to)2653-2663
Number of pages11
ISSN0304-4165
DOIs
Publication statusPublished - 2 Jul 2013

ID: 48063098