vanO, a new glycopeptide resistance operon in environmental Rhodococcus equi isolates
Research output: Contribution to journal › Journal article › Research › peer-review
We describe sequence and gene organization of a new glycopeptide resistance operon (vanO) in Rhodococcus equi from soil. The vanO operon has low homology to enterococccal van operons and harbors a vanHOX cluster transcribed in opposite direction to the vanS-vanR regulatory system and comprised between three open reading frames with unknown function. This finding has clinical interest since glycopeptides are used to treat R. equi infections and resistance has been reported in clinical isolates.
Original language | English |
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Journal | Antimicrobial Agents and Chemotherapy |
Volume | 58 |
Issue number | 3 |
Pages (from-to) | 1768-1770 |
Number of pages | 3 |
ISSN | 0066-4804 |
DOIs | |
Publication status | Published - 2014 |
ID: 94069068