Aberrant expression of mucin core proteins and o-linked glycans associated with progression of pancreatic cancer
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Mucin expression is a common feature of most adenocarcinomas and features prominently in current attempts to improve diagnosis and therapy for pancreatic cancer and other adenocarcinomas. We investigated the expression of a number of mucin core proteins and associated O-linked glycans expressed in pancreatic adenocarcinoma-sialyl Tn (STn), Tn, T antigen, sialyl Lewis A (CA19-9), sialyl Lewis C (SLeC), Lewis X (LeX), and sialyl LeX (SLeX)-during the progression of pancreatic cancer from early stages to metastatic disease.
Original language | English |
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Journal | Clinical Cancer Research |
Volume | 19 |
Issue number | 8 |
Pages (from-to) | 1981-93 |
Number of pages | 13 |
ISSN | 1078-0432 |
DOIs | |
Publication status | Published - 15 Apr 2013 |
ID: 47682974