Ultraviolet A1 phototherapy for mycosis fungoides
Research output: Contribution to journal › Journal article › Research › peer-review
Background. Mycosis fungoides (MF) is the most common form of primary cutaneous lymphoma, and is characterized by a malignant proliferation of CD4+ cells. Psoralen ultraviolet A (PUVA) irradiation is the most common treatment for cutaneous lesions. However, PUVA carries the risk of adverse reactions to psoralens and long-term risk of skin cancer. UVA1 may be a safer alternative. Aim. To assess the efficacy of UVA1 phototherapy in patients with early-stage MF (T1-T2). Methods. Four patients with early-stage MF were treated with 1630-2710 J/cm(2) UVA1 given in 29-40 fractions, and the effect was assessed by clinical examination and by high-resolution ultrasonography. Results. Complete clinical remission of MF was achieved in all cases. Conclusions. This preliminary report indicates that UVA1 phototherapy might be an efficient treatment for early-stage MF.
Original language | English |
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Journal | Clinical and Experimental Dermatology |
Volume | 38 |
Issue number | 2 |
Pages (from-to) | 126-30 |
Number of pages | 5 |
ISSN | 0307-6938 |
DOIs | |
Publication status | Published - 2013 |
ID: 48455500