Array-based genomic screening at diagnosis and during follow-up in chronic lymphocytic leukemia
Research output: Contribution to journal › Journal article › Research › peer-review
High-resolution genomic microarrays enable simultaneous detection of copy-number aberrations such as the known recurrent aberrations in chronic lymphocytic leukemia [del(11q), del(13q), del(17p) and trisomy 12], and copy-number neutral loss of heterozygosity. Moreover, comparison of genomic profiles from sequential patients' samples allows detection of clonal evolution.
Original language | English |
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Journal | Haematologica |
Volume | 96 |
Issue number | 8 |
Pages (from-to) | 1161-9 |
Number of pages | 9 |
ISSN | 0390-6078 |
DOIs | |
Publication status | Published - 2011 |
ID: 40153497