Stratum corneum lipids, skin barrier function and filaggrin mutations in patients with atopic eczema
Research output: Contribution to journal › Journal article › Research › peer-review
Prior to the discovery of filaggrin (FLG) mutations, evidence for an impaired skin barrier in atopic dermatitis (AD) has been documented, and changes in ceramide profile, altered skin pH and increased trans-epidermal water loss (TEWL) in patients with AD have been reported. Until now, no studies have analysed stratum corneum (SC) lipids combined with skin barrier parameters in subjects of known FLG genotype.
| Original language | English |
|---|---|
| Journal | Allergy: European Journal of Allergy and Clinical Immunology |
| Volume | 65 |
| Issue number | 7 |
| Pages (from-to) | 911-8 |
| Number of pages | 8 |
| ISSN | 0105-4538 |
| DOIs | |
| Publication status | Published - 1 Jul 2010 |
ID: 34090352