Effect of the SK/IK channel modulator 4,5-dichloro-1,3-diethyl-1,3-dihydro-benzoimidazol-2-one (NS4591) on contractile force in rat, pig and human detrusor smooth muscle

Research output: Contribution to journalJournal articleResearchpeer-review

  • Jens Steen Nielsen
  • Frederik Rode
  • Mette Rahbek
  • Karl-Erik Andersson
  • Lars Christian Rønn
  • Kirsten Bouchelouche
  • Jorgen Nordling
  • Pierre Bouchelouche
• To investigate the importance of small (SK)- and intermediate (IK)-conductance Ca2(+) -activated K(+) channels on bladder function, by studying the effects of 4,5-dichloro-1,3-diethyl-1,3-dihydro-benzoimidazol-2-one (NS4591), a new modulator of SK/IK channels, on contractions induced by electrical field stimulation (EFS) and carbachol in rat, pig and human detrusor.
Original languageEnglish
JournalB J U International (Print)
Volume108
Issue number5
Pages (from-to)771-7
Number of pages7
ISSN1464-4096
DOIs
Publication statusPublished - 2011

ID: 40185540