MicroRNA-regulated non-viral vectors with improved tumor specificity in an orthotopic rat model of hepatocellular carcinoma
Research output: Contribution to journal › Journal article › Research › peer-review
In hepatocellular carcinoma (HCC), tumor specificity of gene therapy is of utmost importance to preserve liver function. MicroRNAs (miRNAs) are powerful negative regulators of gene expression and many are downregulated in human HCC. We identified seven miRNAs that are also downregulated in tumors in a rat hepatoma model (P
| Original language | English |
|---|---|
| Journal | Gene Therapy |
| Volume | 20 |
| Pages (from-to) | 1006-1013 |
| Number of pages | 8 |
| ISSN | 0969-7128 |
| DOIs | |
| Publication status | Published - 30 May 2013 |
ID: 47315946