Four days of muscle disuse impairs single fiber contractile function in young and old healthy men

Research output: Contribution to journalJournal articleResearchpeer-review

  • Lars G Hvid
  • Charlotte Suetta
  • Per Aagaard
  • Kjær, Michael
  • Ulrik Frandsen
  • Niels Ortenblad
The purpose of the study was to investigate the effects of 4days of disuse (knee brace) on contractile function of isolated vastus lateralis fibers (n=486) from 11 young (24.3±0.9yrs) and 11 old (67.2±1.0yrs) healthy men having comparable levels of physical activity. Prior to disuse single fiber specific force (maximal Ca(2+)-activated force per cross-sectional area) was lower in MHC I vs. IIa fibers (p
Original languageEnglish
JournalExperimental Gerontology
Volume48
Issue number2
Pages (from-to)154-161
Number of pages8
ISSN0531-5565
DOIs
Publication statusPublished - 2013

ID: 48499428