Quantification of thiols and disulfides
Research output: Contribution to journal › Review › Research › peer-review
Disulfide bond formation is a key posttranslational modification, with implications for structure, function and stability of numerous proteins. While disulfide bond formation is a necessary and essential process for many proteins, it is deleterious and disruptive for others. Cells go to great lengths to regulate thiol-disulfide bond homeostasis, typically with several, apparently redundant, systems working in parallel. Dissecting the extent of oxidation and reduction of disulfides is an ongoing challenge due, in part, to the facility of thiol/disulfide exchange reactions.
Original language | English |
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Journal | BBA General Subjects |
Volume | 1840 |
Issue number | 2 |
Pages (from-to) | 838-846 |
Number of pages | 9 |
ISSN | 0304-4165 |
DOIs | |
Publication status | Published - 2014 |
Bibliographical note
Current methods to study reactive oxygen species - pros and cons
ID: 93948523