A PGC-1α- and muscle fibre type-related decrease in markers of mitochondrial oxidative metabolism in skeletal muscle of humans with inherited insulin resistance
Research output: Contribution to journal › Journal article › Research › peer-review
Insulin resistance in obesity and type 2 diabetes is related to abnormalities in mitochondrial oxidative phosphorylation (OxPhos) in skeletal muscle. We tested the hypothesis that mitochondrial oxidative metabolism is impaired in muscle of patients with inherited insulin resistance and defective insulin signalling.
| Original language | English |
|---|---|
| Journal | Diabetologia |
| Volume | 57 |
| Issue number | 5 |
| Pages (from-to) | 1006-1015 |
| Number of pages | 10 |
| ISSN | 0012-186X |
| DOIs | |
| Publication status | Published - 2014 |
ID: 99123126