Can flow-volume loops be used to diagnose exerciseinduced laryngeal obstructions? A comparison study examining the accuracy and inter-rater agreement of flowvolume loops as a diagnostic tool

Research output: Contribution to journalJournal articlepeer-review

BACKGROUND: Pre- and post-exercise flow-volume loops are often recommended as an easy non-invasive method for diagnosing or excluding exercise-induced laryngeal obstructions in patients with exercise-related respiratory symptoms. However, at present there is no evidence for this recommendation.

AIMS: To compare physician evaluated pre- and post-exercise flow-volume loops and flow data with laryngoscopic findings during exercise.

METHODS: Data from 100 consecutive exercise tests with continuous laryngoscopy during the test were analysed. Laryngoscopic images were compared with the corresponding pre- and post-exercise flow-volume loops assessed by four separate physicians and with data from the loops (forced inspiratory flow (FIF) at 25% vs. FIF at 75% of forced inspiratory vital capacity (FIVC), forced expiratory flow at 50% of forced expiratory volume vs. FIF at 50% of FIVC, and FIVC vs. FIF at 50% of FIVC).

RESULTS: There was no significant association between the laryngoscopic findings and the flow-volume data. There was no agreement between the four physicians in their assessment of the flow-volume loops (kappa <0.00), and none of the individual physician's assessments were significantly associated with the laryngoscopic findings.

CONCLUSIONS: Exercise-induced laryngeal obstructions cannot be diagnosed or excluded by physician evaluated pre- and post-exercise flow-volume loops or flow data alone.

Original languageEnglish
JournalPrimary Care Respiratory Journal
Volume22
Issue number3
Pages (from-to)306-311
Number of pages6
ISSN1471-4418
DOIs
Publication statusPublished - 2013

    Research areas

  • Adolescent, Adult, Airway Obstruction, Child, Cohort Studies, Exercise, Exercise Test, Feasibility Studies, Female, Forced Expiratory Flow Rates, Forced Expiratory Volume, Humans, Inspiratory Capacity, Laryngeal Diseases, Laryngoscopy, Male, Vocal Cord Dysfunction, Young Adult

ID: 119176996