Effect of systematic local infiltration analgesia on postoperative pain in vaginal hysterectomy: a randomized, placebo-controlled trial
Research output: Contribution to journal › Journal article › Research › peer-review
OBJECTIVE: To assess the effect of systematic local infiltration analgesia on postoperative pain in vaginal hysterectomy, and describe the technique in detail.
DESIGN: A randomized, double-blind, placebo-controlled study following the CONSORT criteria.
SETTING: A university hospital.
PATIENTS: Thirty-seven patients undergoing vaginal hysterectomy.
METHODS: Patients received high-volume (50 mL) ropivacaine 0.50% (n = 20) or saline (n = 17) infiltration using a systematic technique ensuring uniform delivery to all tissues incised, handled or instrumented during the procedure.
MAIN OUTCOME MEASURES: Pain, nausea, vomiting and opioid requirements were assessed for 32 h as well as time spent in the post-anesthesia care unit and time to first mobilization.
RESULTS: Pain at rest was significantly reduced after one, four and eight hours in the ropivacaine group (p ≤ 0.001-0.01). Pain during coughing was significantly reduced after one and four hours (p ≤ 0.001 and p ≤ 0.003), and pain during movement was significantly reduced after four hours (p ≤ 0.02). Opioid requirements and time spent in the post-anesthesia care unit were significantly reduced in the ropivacaine group (p < 0.001 and p < 0.001, respectively), as well as the time to first mobilization (p < 0.001).
CONCLUSION: Intra-operative systematic local infiltration analgesia reduces postoperative pain in patients undergoing vaginal hysterectomy, facilities mobilization and improves early recovery.
Original language | English |
---|---|
Journal | Acta Obstetrica et Gynecologica |
Volume | 93 |
Issue number | 3 |
Pages (from-to) | 233-238 |
Number of pages | 6 |
ISSN | 0001-6349 |
DOIs | |
Publication status | Published - Mar 2014 |
- Adult, Aged, Amides, Analgesia, Anesthesia, Local, Anesthetics, Local, Double-Blind Method, Female, Humans, Hysterectomy, Vaginal, Middle Aged, Pain Measurement, Pain, Postoperative, Time Factors
Research areas
ID: 137617250