Genetic, pathological and physiological determinants of transdermal fentanyl pharmacokinetics in 620 cancer patients of the EPOS study

Research output: Contribution to journalJournal articleResearchpeer-review

  • Daniel T Barratt
  • Benedikte Bandak
  • Pål Klepstad
  • Ola Dale
  • Stein Kaasa
  • Christrup, Lona Louring
  • Jonathan Tuke
  • Andrew A Somogyi
This study aimed to investigate whether CYP3A4/5 genetic variants, together with clinical and patient factors, influence serum fentanyl and norfentanyl concentrations and their ratio in cancer pain patients receiving transdermal fentanyl.
Original languageEnglish
JournalPharmacogenetics and Genomics
Volume24
Issue number4
Pages (from-to)185-194
Number of pages10
ISSN1744-6872
Publication statusPublished - 2014

ID: 101829242