Penicillin resistance and serotype distribution of Streptococcus pneumoniae in Ghanaian children less than six years of age
Research output: Contribution to journal › Journal article › Research › peer-review
Background: The objective of this study was to determine the prevalence of nasopharyngeal carriage, serotype distribution, and penicillin resistance of Streptococcus pneumoniae in children 2 mu g/ml and were classified as fully penicillin resistant with 45% of the isolates having intermediate resistance. Conclusions: These findings indicate that the 13-valent pneumococcal conjugate vaccine (PCV-13) recently introduced in Ghana will cover 48% and 51% of the serotypes identified in Accra and Tamale, respectively. The 23-valent pneumococcal polysaccharide vaccine (PPV-23) will cover 54% of all serotypes detected. The two penicillin resistant isolates (MIC 32 mu g/ml) were serotypes included in both PCV-13 and PPV-23. A nationwide monitoring system of penicillin susceptibility patterns and pneumococcal serotypes is recommended.
Original language | English |
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Journal | B M C Infectious Diseases |
Volume | 13 |
Pages (from-to) | 1-7 |
Number of pages | 7 |
ISSN | 1471-2334 |
DOIs | |
Publication status | Published - 2013 |
ID: 119588999