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Endothelial glycocalyx: shedding light on malaria pathogenesis

Publikation: Forskning - peer reviewTidsskriftartikel

Casper Hempel, Erica M Pasini, Jørgen A L Kurtzhals

Malaria is estimated to kill 438 000 people annually, mostly due to severe malaria, which is closely associated with microcirculatory vasculopathy, although its pathogenesis remains incompletely understood. Here, we propose that the largely ignored glycocalyx of the vascular endothelium plays an important role in facilitating the pathogenesis of severe malaria.

OriginalsprogEngelsk
TidsskriftTrends in Molecular Medicine
Vol/bind22
Tidsskriftsnummer6
Sider (fra-til)453-457
Antal sider5
ISSN1471-4914
DOI
StatusUdgivet - jun. 2016

ID: 162190707