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Kristian Helin

Kristian Helin

direktør, professor


  1. 2017
  2. Udgivet

    EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas. / Mohammad, Faizaan; Weissmann, Simon; Leblanc, Benjamin Olivier; Pandey, Deo Prakash; Højfeldt, Jonas Westergaard; Comet, Itys; Zheng, Chunqin; Johansen, Jens Vilstrup; Rapin, Nicolas Philippe Jean-Pierre; Porse, Bo Torben; Tvardovskiy, Andrey; Jensen, Ole N; Olaciregui, Nagore G.; Lavarino, Cinzia; Suñol, Mariona; de Torres, Carmen; Mora, Jaume; Carcaboso, Angel M.; Helin, Kristian.

    I: Nature Medicine, Vol. 23, Nr. 4, 04.2017, s. 483-492.

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

  3. 2016
  4. Udgivet

    Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells. / Agger, Karl; Miyagi, Satoru; Pedersen, Marianne Terndrup; Kooistra, Susanne M; Johansen, Jens Vilstrup; Helin, Kristian.

    I: Genes & Development, Vol. 30, Nr. 11, 01.06.2016, s. 1278-88.

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

  5. Udgivet

    Maintaining cell identity : PRC2-mediated regulation of transcription and cancer. / Comet, Itys; Riising, Eva M; Leblanc, Benjamin; Helin, Kristian.

    I: Nature Reviews. Cancer, Vol. 16, 12.2016, s. 803–810.

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

  6. Udgivet

    Jarid2 binds mono-ubiquitylated H2A lysine 119 to mediate crosstalk between Polycomb complexes PRC1 and PRC2. / Cooper, Sarah; Grijzenhout, Anne; Underwood, Elizabeth; Ancelin, Katia; Zhang, Tianyi; Nesterova, Tatyana B; Anil-Kirmizitas, Burcu; Bassett, Andrew; Kooistra, Susanne M; Agger, Karl; Helin, Kristian; Heard, Edith; Brockdorff, Neil.

    I: Nature Communications, Vol. 7, 13661, 28.11.2016.

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

  7. Udgivet

    A novel oncogenic BTK isoform is overexpressed in colon cancers and required for RAS-mediated transformation. / Grassilli, E; Pisano, F; Cialdella, A; Bonomo, S; Missaglia, C; Cerrito, M G; Masiero, L; Ianzano, L; Giordano, F; Cicirelli, V; Narloch, R; D'Amato, F; Noli, B; Ferri, G L; Leone, B E; Stanta, G; Bonin, S; Helin, K; Giovannoni, R; Lavitrano, M.

    I: Oncogene, Vol. 35, 25.01.2016, s. 4368-4378.

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

  8. Udgivet

    Regional tumour glutamine supply affects chromatin and cell identity. / Højfeldt, Jonas W; Helin, Kristian.

    I: Nature Cell Biology, Vol. 18, Nr. 10, 28.09.2016, s. 1027-9.

    Publikation: ForskningLetter

  9. Udgivet

    Role of the Polycomb Repressive Complex 2 (PRC2) in Transcriptional Regulation and Cancer. / Laugesen, Anne; Højfeldt, Jonas Westergaard; Helin, Kristian.

    I: Cold Spring Harbor Perspectives in Medicine, Vol. 6, Nr. 9, a026575, 2016.

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

  10. Udgivet

    Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development. / Pedersen, Marianne Terndrup; Kooistra, Susanne Marije; Radzisheuskaya, Aliaksandra; Laugesen, Anne; Johansen, Jens Vilstrup; Hayward, Daniel Geoffrey; Nilsson, Jakob; Agger, Karl; Helin, Kristian.

    I: E M B O Journal, Vol. 35, Nr. 14, 15.07.2016, s. 1550-64.

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

  11. Udgivet

    Optimizing sgRNA position markedly improves the efficiency of CRISPR/dCas9-mediated transcriptional repression. / Radzisheuskaya, Aliaksandra; Shlyueva, Daria; Müller, Iris; Helin, Kristian.

    I: Nucleic acids research, Vol. 44, Nr. 18, e141, 28.06.2016.

    Publikation: Forskning - fagfællebedømtTidsskriftartikel

  12. Udgivet

    Role of TET enzymes in DNA methylation, development, and cancer. / Rasmussen, Kasper Dindler; Helin, Kristian.

    I: Genes & Development, Vol. 30, Nr. 7, 01.04.2016, s. 733-50.

    Publikation: Forskning - fagfællebedømtReview

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ID: 927363